Polymyalgia Rheumatica

Posts Tagged ‘systematic’

Conclusions  The scarcity of randomized trials and the high level of heterogeneity of studies on PMR therapy do not allow firm conclusions to be drawn. However, PMR remission seems to be achieved with prednisone treatment at a dose of 15 mg/d in most patients, and reductions below 10 mg/d should preferably follow a tapering rate of less than 1 mg/mo. Methotrexate seems to exert glucocorticoid-sparing properties. (Source: Archives of Internal Medicine)
MedWorm: Polymyalgia Rheumatica

Source: Arch Internal Med
Area: News
A systematic review of the evidence on treatment of polymyalgia rheumatica concludes that there is a scarcity of controlled trials and significant heterogeneity in those that exist; as a result, it is not possible to draw firm conclusions on the optimum treatment.
 
Polymyalgia rheumatica (PMR) is a syndrome that occurs in people aged over 50 and presents with morning stiffness and aching in the shoulder and pelvic girdles, with signs of systemic inflammation. Systemic corticosteroids are the standard treatment, however there have been no systematic summaries of the evidence for corticosteroid or other therapy: the authors of this review aimed to determine whether there was evidence to indicate the optimum corticosteroid, dose, and dose reduct…

Conclusion  We found overall valuable diagnostic performances for FDG PET against reference criteria. Standardized FDG uptake criteria
are needed to optimize these diagnostic performances.

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