Polymyalgia Rheumatica

Posts Tagged ‘Rheumatica’

Stifel Nicolaus Sees An Opportunity In Horizon Pharma Shares
It also develops Lodotra, which is under Phase 2 clinical trial for the treatment of polymyalgia rheumatica. Lodotra is already approved in 16 European countries and is currently under FDA review (PDUFA) which the company anticipates an approval …
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Conclusion
Antibodies against the ferritin peptide were present in up to 92% of untreated, active GCA and PMR patients. They can be useful as a diagnostic marker of PMR and GCA. (Source: Annals of the Rheumatic Diseases)

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Authors: Schmidt WA
Myalgias most commonly occur in polymyalgia rheumatica (PMR). About 45% of patients with giant cell arteritis present with symptoms of PMR. Other vasculitides may also lead to arthralgia and myalgia. While shoulder and pelvic pain is characteristic for PMR pain often also occurs in the back of the neck and in the region of the thoracic spine. In addition, patients often present with malaise, morning stiffness and weight loss. CRP and ESR are elevated. Ultrasound and MRI delineate minor synovitis, tenosynovitis and bursitis in the shoulder. Hip joint synovitis and trochanteric bursitis are also commonly seen. PMR should be distinguished from rheumatoid arthritis. The initial treatment comprises a prednisolone dose of 15-25 mg/day, followed by a weekly decrease of 1-2…
MedWorm: Polymyalgia Rheumatica

Title: Polymyalgia RheumaticaCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 2/15/2012 (Source: MedicineNet Senior Health General)
MedWorm: Polymyalgia Rheumatica

Conclusions: Because of the varied and vague symptom presentations of PMR and GCA, primary healthcare providers often misdiagnose these pathologies, delaying treatment and relief of suffering. Textbooks descriptions often omit supplemental content necessary to understand the intricacies of the presenting symptoms, diagnostic tests needed for work‐up, and specific treatment for these overlapping pathologies.Implications for practice: Because PMR and GCA often present in the primary care setting, NPs must maintain a high index of suspicion when a patient over 60 years of age presents with vague complaints such as headache, weakness, anorexia, and malaise. Arriving at an accurate diagnosis in a timely fashion will lead to appropriate treatment and minimize patient suffering. (Source: Journa…

Content Type Journal ArticleCategory Letter to the EditorDOI 10.1007/s00277-009-0779-6Authors
C. Durant, CHU Hotel Dieu Service de Médecine Interne 1, place Alexis Ricordeau 44093 Nantes Cedex FranceB. Hervier, CHU Hotel Dieu Service de Médecine Interne 1, place Alexis Ricordeau 44093 Nantes Cedex FranceC. Ansquer, CHU Hotel Dieu Nuclear Medicine Nantes FranceA. Masseau, CHU Hotel Dieu Service de Médecine Interne 1, place Alexis Ricordeau 44093 Nantes Cedex FranceM. Hamidou, CHU Hotel Dieu Service de Médecine Interne 1, place Alexis Ricordeau 44093 Nantes Cedex France

Journal Annals of HematologyOnline ISSN 1432-0584Print ISSN 0939-5555 (Source: Annals of Hematology)
MedWorm: Polymyalgia Rheumatica

Title: Polymyalgia RheumaticaCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 2/15/2012 (Source: MedicineNet Migraine General)

CONCLUSION: Expression of GR and the presence of CD20-, CD3-, CD4-, CD8-, CD68-, CD138-positive cells and antigen-presenting cells differ between GCA and PMR. The presence of CD68-positive cells and the extent of GR-staining in chronic inflammation are suitable to predict complete remission in GCA.
PMID: 19684157 [PubMed - as supplied by publisher] (Source: J Rheumatol)
MedWorm: Polymyalgia Rheumatica