Polymyalgia Rheumatica

Open Question: i have been taking prednisolone for four years for polymyalgia. recently I have been getting sharp pains back?

admin — Fri, 03 Sep 2010 13:01:03 +0000

How can I tell if it is muscle or bone

Open Question: Is it possible for people with polymyalgia rheumatica to have sharp pain in all the finger bones?
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Resolved Question: I would like to answer a subject relating to prednisolone and alcohol?
It is a question that has long ago been resolved but, I am taking 10mg of prednisolone a day for p...
Is It Rheumatoid Arthritis, Polymyalgia or What?
by Graham Kelly What a great disease arthritis is. Is there any other illness where the experts w...
Resolved Question: Has anyone had Polymyalgia Rheumatica?
Resolved Question: Polymyalgia Rheumatica and Prednisolone ?

Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica

admin — Fri, 03 Sep 2010 05:04:48 +0000

(Source: Arthritis and Rheumatism)MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.

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Circulating cytokines in active polymyalgia rheumatica
Conclusions: Active PMR is characterised by increased serum levels of IL6, but not of other proinfla...
Giant cell arteritis and polymyalgia rheumatica: role of cytokines in the pathogenesis and implications for treatment.
Conclusion: Further studies are needed to evaluate the role of circulating cytokines in PMR and GCA....
Procalcitonin at the onset of giant cell arteritis and polymyalgia rheumatica: the gracg prospective study
Conclusions. These results are not in favour of a bacterial trigger for GCA or PMR. Increased PCT le...
Insulin sensitivity and related cytokines, chemokines, and adipokines in polymyalgia rheumatica.
Serum interleukin-6 receptor in polymyalgia rheumatica: a potential marker of relapse/recurrence risk

Concise guidance: diagnosis and management of polymyalgia rheumatica.

admin — Fri, 27 Aug 2010 17:43:54 +0000

Authors: Bhaskar D
Polymyalgia rheumatica (PMR) is among the most common reasons for long-term steroid prescription with great heterogeneity in presentation, response to steroids and disease course. The British Society for Rheumatology and the British Health Professionals in Rheumatology have recently published guidelines on management of PMR. The purpose of this concise guidance is to draw attention to the full guidelines and provide a safe and specific diagnostic process with advice on management and monitoring–specifically targeted at general practitioners, general physicians and rheumatologists.
PMID: 20726461 [PubMed - in process] (Source: Clinical Medicine)

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BSR and BHPR guidelines for management of polymyalgia rheumatica
Source: Rheumatology, BMJ Area: News The British Society for Rheumatology (BSR) and the British Hea...
Polymyalgia rheumatica and temporal arteritis: evidence and guidelines for diagnosis and management in older people
by Richard Frearson, Tim Cassidy, Julia Newton Polymyalgia rheumatica and temporal arteritis co...
Polymyalgia rheumatica and giant-cell arteritis (william cayley md mdiv)
This Powerpoint presentation gives an overview of the pathophysiology, diagnosis, and management of ...
Is a diagnosis of temporal arteritis still feasible if the…
Management of polymyalgia rheumatica

Lack of Steroid Response Flags Biopsy Candidates in PMR

admin — Fri, 20 Aug 2010 19:45:10 +0000

ROME â€” Polymyalgia rheumatica may be the presenting manifestation of silent giant cell arteritis, and therein lies a diagnostic dilemma: Which patients need a temporal artery biopsy? (Source: Rheumatology News)

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Lack of Association Between STAT4 Gene Polymorphism and Biopsy-proven Giant Cell Arteritis.
CONCLUSION: Our results do not support a major role of the STAT4 rs7574865 gene polymorphism in susc...
Lack of Association Between the rs6920220 (G/A) Polymorphism of the 6q23 Region and Biopsy-proven Giant Cell Arteritis.
CONCLUSION: Our results show no involvement of this 6q23/TNFAIP3 gene region SNP in the susceptibili...
Lack of Association Between IRF5 Gene Polymorphisms and Biopsy-proven Giant Cell Arteritis.
CONCLUSION: Our results showed no association of IRF5 rs2004640 and CGGGG insertion/deletion polymor...
Diagnosis and treatment of polymyalgia rheumatica - Tips from Other Journals
Steroid-induced crisis and rhabdomyolysis in a patient with pheochromocytoma: a case report and review.

Polymyalgia Rheumatica: Steroids and Beyond: Lower doses of prednisone and a greater use of biologics are on the PMR treatment horizon.

admin — Fri, 20 Aug 2010 19:45:10 +0000

ROME â€” A newly launched clinical trial is examining whether adrenal insufficiency contributes to the pathology of polymyalgia rheumatica. If the study yields data to support the adrenal insufficiency hypothesis, it’s quite possible that doses lower than the currently recommended 15-20 mg/day would achieve equal disease control with fewer steroid side effects, according to Dr. Marco A. Cimmino, one of the investigators. (Source: Rheumatology News)

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Temporal Arteritis and Polymyalgia Rheumatica
by American Family Physician What is temporal arteritis? Temporal arteritis is the most common...
Diagnosis and treatment of polymyalgia rheumatica - Tips from Other Journals
by Anne D. Walling Polymyalgia rheumatica primarily affects persons of northern European descent ...
Resolved Question: What can you tell me about the Management of acute Polymyalgia with Prednisone induced Cushing’s Syndrome ?
I've had very bad Polymyalgia for a couple of years. I was only diagnosed a year ago. I was placed...
Voting Question: Professional Health Advice Please?
Corticosteroids in Patients with Polymyalgia Rheumatica

Candidate PMR Criteria Are a Work in Progress

admin — Fri, 20 Aug 2010 19:45:10 +0000

ROME â€” Candidate international consensus criteria for diagnosis of polymyalgia rheumatica performed well in their first large prospective validation study. But there’s room for further improvement with tweaking of the criteria, according to Dr. Bhaskar Dasgupta, the project leader. (Source: Rheumatology News)MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.

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Polymyalgia rheumatica in primary care: a cohort study of the diagnostic criteria and outcome
Background. Polymyalgia rheumatica (PMR) is common and is usually diagnosed and managed in primary c...
Resolved Question: Polymyalgia and im 23?
I'm 23 and i am getting this, there is no family history. I know these things start somewhere but...
Epidemiological studies in incidence, prevalence, mortality, and comorbidity of the rheumatic diseases
Epidemiology is the study of the distribution and determinants of disease in human populations. Ove...
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Ultrasonography in early assessment of elderly patients with polymyalgic symptoms: a role in predicting diagnostic outcome?

admin — Wed, 28 Jul 2010 09:11:46 +0000

Conclusions: US and PDUS can be useful in distinguishing, at onset of disease, pure PMR from other diseases mimicking this condition.
PMID: 20653466 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.

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Small-vessel vasculitis surrounding an uninflamed temporal artery: a new diagnostic criterion for polymyalgia rheumatica?
To assess the prevalence and clinical significance of small-vessel vasculitis (SVV) surrounding an u...
Serum interleukin-6 receptor in polymyalgia rheumatica: a potential marker of relapse/recurrence risk
To investigate the modulation of systemic levels of soluble interleukin-6 receptor (sIL-6R) and solu...
BSR and BHPR guidelines for management of polymyalgia rheumatica
Source: Rheumatology, BMJ Area: News The British Society for Rheumatology (BSR) and the British Hea...
Polymyalgia rheumatica in primary care: a cohort study of the diagnostic criteria and outcome
An elderly lady with a painful swollen face.

Open Question: Polymyalgia, and prednisone?

admin — Sun, 11 Jul 2010 13:03:56 +0000

A few months ago I had a sinus infection, and the doctor prescribed prednisone. Almost immediately I noticed that I felt better than I had in years. I had constantly felt like I had been run over by a truck, but it had developed so gradually that I wasn’t really aware that I was sore, arms and legs falling asleep, muscles super tense etc. The prescription was for a tapering dose, starting at ten pills a day. When I got down to seven pills a day, the symptoms started returning, so after I finished the supply, I went back to the doctor. He said that immediate response to prednisone was one of the indicators of a rheumatic disease, possibly polymyalgia. Does anyone have information about this disease, and about the co relation between the time prednisone acts on pain, and diagnosis of rheumatic diseases?

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Open Question: Prednisone … and ankle swelling….?
My mom started on 20 mg. of Prednisone in mid-Novermber, and after 3 weeks was reduced to 10 mg. S...
Open Question: Prednisone and swollen ankles?
She was prescribed the Prednisone for PMR (polymyalgia rheumatica).... My mom started on 20 mg. of...
Open Question: I have Polymyalgia and been on Prednisone for 12 mths. Pred lowers your resistance to infections so can it …?
can it cause an infection like herpes? Read full story
Resolved Question: What are side effects of prednisone ?
Resolved Question: Question about Methotrexate?

Insulin sensitivity and related cytokines, chemokines, and adipokines in polymyalgia rheumatica.

admin — Sun, 11 Jul 2010 13:03:55 +0000

Conclusion: IS is decreased in PMR, probably reflecting abnormal cytokine and adipokine levels. Treatment with prednisolone improves IS along with normalization of cytokine and adipokine levels and physical activity.
PMID: 20615159 [PubMed - as supplied by publisher] (Source: Scandinavian Journal of Rheumatology)MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.

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Changes in adiponectin and leptin concentrations during glucocorticoid treatment: a pilot study in patients with polymyalgia rheumatica
This study is concerned with an evaluation of the effects of glucocorticoids (GC) on adiponectin and...
Giant cell arteritis and polymyalgia rheumatica: role of cytokines in the pathogenesis and implications for treatment.
Conclusion: Further studies are needed to evaluate the role of circulating cytokines in PMR and GCA....
Circulating cytokines in active polymyalgia rheumatica
Conclusions: Active PMR is characterised by increased serum levels of IL6, but not of other proinfla...
Increased muscle interstitial levels of inflammatory cytokines in polymyalgia rheumatica
Familial associations of rheumatoid arthritis with autoimmune diseases and related conditions

A case of apoplectic lymphocytic hypophysitis complicated by polymyalgia rheumatica

admin — Fri, 04 Jun 2010 18:27:23 +0000

Abstract A case of apoplectic lymphocytic hypophysitis complicated by polymyalgia rheumatica (PMA) is described. A 72-year-old man
was admitted to our hospital due to severe headache. Two months prior to admission, the patients had exhibited recent-onset
stiffness and myalgia of shoulder and pelvic girdle that was compatible with PMR. Magnetic resonance imaging revealed a mass
lesion in the pituitary fossa with focal hemorrhage. Endocrinologic studies demonstrated hypopituitarism. The headache and
myalgia were improving with corticosteroid treatment; however, a trans-sphenoidal surgery was performed due to visual field
loss. A white-colored mass was resected, and histologic examination showed diffuse infiltration of lymphocytes and plasma
cells consistent with lymphocytic …MedWorm Message: Register for MedMatcha, MedWorm’s medical advertising network, and receive $5 free advertising.

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A case of cold agglutinin disease in the course of treatment for polymyalgia rheumatica
Abstract A 60-year-old male who had been treated for polymyalgia rheumatica (PMR) with Ra...
Two-month suspension recommended for part-time judge in pot case
By The Associated Press MONTPELIER - A lawyer whose marijuana-possession case triggered debate over ...
Giant cell arteritis of the breast: a case report with a review of literatures.
We report a case of GCA affecting the breast and review previous reports on this condition in an att...
Giant cell arteritis presenting as a breast lesion: report of a case and review of the literature.
Polymyalgia rheumatica prevalence in a population-based sample