Archive for the ‘Uncategorized’ Category
Induction of Remission is Difficult due to Frequent Relapse during Tapering Steroids in Korean Patients with Polymyalgia Rheumatica.
April 16th, 2012 | 
Author: Authors: Kim HA, Lee J, Ha YJ, Kim SH, Lee CH, Choi HJ, Baek HJ, Lim MJ, Park W, Choi S, Hong YS, Lee YH, Koh BR, Suh CH
Abstract
Polymyalgia rheumatica is an inflammatory disease affecting elderly and involving the shoulder and pelvic girdles. No epidemiological study of polymyalgia rheumatica was conducted in Korea. We retrospectively evaluated patients with polymyalgia rheumatica followed up at the rheumatology clinics of 10 tertiary hospitals. In total 51 patients, 36 patients (70.6%) were female. Age at disease onset was 67.4 yr. Twenty-three patients (45.1%) developed polymyalgia rheumatica in winter. Shoulder girdle ache was observed in 45 patients (90%) and elevated erythrocyte sedimentation rate (> 40 mm/h) in 49 patients (96.1%). Initial steroid dose was 23.3 mg/d pred…
MedWorm: Polymyalgia Rheumatica
Imbalance between endothelial injury and repair in patients with polymyalgia rheumatica: improvement with corticosteroid treatment
Conclusions. Polymyalgia rheumatica is associated with a significant imbalance between endothelial injury and repair, which is dependent on the degree of systemic inflammation. Attenuation of inflammation by short‐term corticosteroid therapy might have a role in limiting endothelial fragmentation and promote endothelial repair. (Source: Journal of Internal Medicine)
MedWorm: Polymyalgia Rheumatica
How to Differentiate Polymyalgia Rheumatica From Temporal Arteritis Or Fibromyalgia
How to Differentiate Polymyalgia Rheumatica From Temporal Arteritis Or Fibromyalgia
There is a lot of confusion about Polymyalgia Rheumatica (PMR) and its relative similarities with Giant Cell Arteritis and Fibromyalgia. So that you can reference for yourself I have quickly profiled these other diseases in the following paragraphs.
Polymyalgia Rheumatica
Title: Polymyalgia RheumaticaCategory: Diseases and ConditionsCreated: 12/31/1997Last Editorial Review: 2/15/2012 (Source: MedicineNet Arthritis General)
MedWorm: Polymyalgia Rheumatica
Polymyalgia – Important Facts That You Should Be Aware Of
Polymyalgia – Important Facts That You Should Be Aware Of
Polymyalgia rheumatica in simple terms is an inflammation of the muscles which occurs mainly in the over fifties, women in particular.
It may come on gradually, or so suddenly that the sufferer is immobilised and in severe pain in a matter of seconds. When a G. P. is consulted and the symptoms have been described, before any intensive testing is done there is usually the simple question asked of the patient, ‘Are you having trouble getting in and out of bed? and if the answer is ‘yes’ it almost always follows that they have got polymyalgia rheumatica.
Provisional diagnostic criteria for polymyalgia rheumatica: Moving beyond clinical intuition?
(Source: Arthritis and Rheumatism)
MedWorm: Polymyalgia Rheumatica
2012 Provisional classification criteria for polymyalgia rheumatica: A European League Against Rheumatism/American College of Rheumatology collaborative initiative
The objective of this study was to develop European League Against Rheumatism/American College of Rheumatology classification criteria for polymyalgia rheumatica (PMR). Candidate criteria were evaluated in a 6‐month prospective cohort study of 125 patients with new‐onset PMR and 169 non‐PMR comparison subjects with conditions mimicking PMR. A scoring algorithm was developed based on morning stiffness >45 minutes (2 points), hip pain/limited range of motion (1 point), absence of rheumatoid factor and/or anti–citrullinated protein antibody (2 points), and absence of peripheral joint pain (1 point). A score ≥4 had 68% sensitivity and 78% specificity for discriminating all comparison subjects from PMR. The specificity was higher (88%) for discriminating shoulder conditions from PM…
Horizon Pharma's Rayos – A No-brainer Or Speculation?
Horizon Pharma's Rayos – A No-brainer Or Speculation?
Lodotra/Rayos is also being investigated as a potential treatment for polymyalgia rheumatica, or PMR, an inflammatory disorder involving aching and stiffness in patients over the age of 50 typically affecting the shoulders and arms, in a phase II study …
Read more on RTT News
Artery inflammation leads to many symptoms
Artery inflammation leads to many symptoms
The artery inflammation comes from an infiltration of artery walls with cells of the immune system. What triggers this invasion is not known with certitude. Temporal arteritis has another name: giant cell arteritis. Temporal arteritis is an illness of …
Read more on Sarasota Herald-Tribune
Anti-TNF therapy for polymyalgia rheumatica: report of 99 cases and review of the literature
This study
demonstrated a good clinical and laboratory response to anti-TNF therapy in patients with PMR, with or without glucocorticoid.
Content Type Journal ArticleCategory Case Based ReviewPages 1-5DOI 10.1007/s10067-011-1914-zAuthors
Nádia Emi Aikawa, Rheumatology Division, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455-3o andar-Reumatologia, sala 3190, São Paulo, 01246-903 BrazilRosa Maria Rodrigues Pereira, Rheumatology Division, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455-3o andar-Reumatologia, sala 3190, São Paulo, 01246-903 BrazilLaís Lage, Rheumatology Division, Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo, Av. Dr. Arnaldo, 455-… Read the rest of this entry »